Women with hyperprolactinaemia usually present with menstrual abnormalities: amenorrhoea or oligomenorrhoea; or regular cycles with infertility. Occasionally, patients may present with menorrhagia. Men often present late in the course of the disease with symptoms of expansion of their pituitary tumour, or symptoms from secondary adrenal or thyroid failure (see Hypothyroidism). These men, however, have usually been impotent for many years before their presentation.
Occasionally, the syndrome may occur in prepubertal or peripubertal children, when it may present with delayed or arrested puberty.
